Mcq part 5

Mcq part 5

Q.Probiotics, which are cultures of potentially beneficial gut microflora bacteria, have been studied in the primary prevention of which of the following diseases?
A. Celiac disease
B. Atopic dermatitis
C. Psoriasis
D. Cutaneous T-cell lymphoma
E. Asthma

ANS: B

Q.A potentially dangerous side effect of spironolactone is:
A. Hypokalemia
B. Hyperkalemia
C. Hypercalcemia
D. Hyponatremia
E. Hypernatremia

ANS: B

Q.Narrowband UVB is effective for psoriasis and can be used in pregnancy and in childhood. It is also less carcinogenic than PUVA. The wavelength of narrowband UVB is:
A. 311-312nm
B. 315-317nm
C. 300-302nm
D. 318-320nm
E. 317-319nm

ANS: A

Q.Fluorescent UVA bulbs used for phototesting or PUVA therapy have a peak emission at:
A. 254 nm
B. 311 nm
C. 312 nm
D. 352 nm
E. 468 nm

ANS: D

Q.What bacteria may play a role in the pathogenesis of Morphea?
A. B. burgdorferi
B. H. pylori
C. E. coli
D. S. aureus
E. S. enteritidis

ANS: A

Q.Which HLA type is more commonly associated with balnitis circinata ?
A. HLA-B7
B. HLA-B15
C. HLA-B27
D. HLA-B51
E. HLA-DR4

ANS: C

Q.Human orf, also known as ecthyma contagiosum, was diagnosed in a 43 year old farmer by an astute resident dermatologist. Patient presented with a dome shaped, firm bulla with an umbilicated crust. Which of the following virus is responsible?
A. Pox virus
B. HHV-8
C. Parapox virus
D. HPV 5,8
E. Mycobacterium bovis

ANS: C

Q.A child presents with a 1 cm yellow-red nodule on the face. Pathology shows Touton giant cells.
What is the most frequent site of extracutaneous involvement in this disease?
A. Eye
B. Lung
C. Bone
D. CNS
E. Visceral

ANS: A

Q.Mast cells are derived from bone marrow ____+ cells?
A. CD3
B. CD6
C. CD20
D. CD34
E. CD68

ANS: D

Q.Sebaceous glands:
A. Respond to chemical stimuli such as hormones
B. Respond to cholinergic neural activity, exclusively
C. Respond to adrenergic neural activity, exclusively
D. Respond to both adrenergic and cholinergic stimuli
E. Respond to the local release of cytokines from inflammatory cells

ANS: A

Q.Retinoids upregulate transcription of which types of collagen?
A. 1 and 3
B. 1 and 4
C. 1 and 7
D. 3 and 7
E. 4 and 7

ANS: C

Q.Defects in what kind of structural protein lead to pyloric atresia associated with junctional
epidermolysis bullosa:
A. Collagen
B. Elastin
C. Loricrin
D. Integrin
E. Plectin

ANS: D

Q.Meibomian glands are:
A. Eccrine glands localized to the vermillion
border of the lips
B. Sebaceous glands found on the areola of the
breast
C. Sebaceous glands found on the eyelids
D. Apocrine glands found in the anogenital
regions

ANS: C

Q.Regarding the stratum germinativum (basale):
A. Intermediate filaments in basal cells insert
into only hemidesmosomes
B. Keratins 1 and 10 are expressed
C. Not all basal cells have the potential to
divide
D. Microfilaments assist in downward
movement of cells
E. Plectins regulate adhesion and initiation of
differentiation.

ANS: C

Q.Which of the following cells are required for wound healing?
A. Neutrophil
B. Macrophage
C. Eosinophil
D. Langerhans cell
E. Lymphocyte

ANS: B

Q.Which of the following is true regarding BPAg1?
A. It is pathogenic in cicatricial pemphigoid
B. It is a member of the plakin family
C. It is pathogenic in pemphigoid gestationis
D. It is not pathogenic in paraneoplastic
pemphigus
E. It coprecipitates with plakoglobin

ANS: B

Q.The antibody target in ocular cicatricial pemphigoid is also mutated in:
A. Junctional epidermolysis bullosa, Herlitz
type
B. Recessive dystrophic epidermolysis bullosa
C. Junctional epidermolysis bullosa with
myotonic dystrophy
D. Dominant dystrophic epidermolysis bullosa
E. Junctional epidermolysis bullosa with
pyloric atresia

ANS: E